World’s first contraceptive vaccine for men has been invented

World's first contraceptive vaccine for men has been invented

For a long time there were only two methods of contraception that were directly related to men. We had to either wear a condom or undergo a surgery called Vasectomy, which closes the drains through which the sperm reaches the penis. Contraceptive pills and gels for men are still being developed.

However, a contraceptive vaccine for men is being introduced soon in India. Will this contraceptive method be successful for men?

Developed by 78-year-old biomedical engineer Sujoy Guha, based in Delhi, it is a single shot vaccine that is injected into the drains that carry the sperm to the penis. The vaccine in combination with local anesthesia is not hormonal, and researchers claim that the vaccine will be effective for 13 years.

After years of testing on humans, this drug called Risug is now ready to be introduced in the market. This medicine is a vaccine that neutralizes sperm. The effects of this medicine are also reversible. However, the second part of the procedure under which the effects of this drug can be reversed has not yet been tested on humans, although it has been successful in animals.

And like other methods, contraceptive injections will not be able to protect against sexually transmitted diseases.

“This contraceptive injection made for men will be world-class,” says RS Sharma, a specialist in the Indian Council of Medical Research in Delhi and the lead researcher on the drug. It is safe and effective and will work for a long time. We hope to be allowed it’s production in the near future. ”

But is it really a reversible contraceptive drug? A lot of questions are being raised in this regard.

Some scientists say that ‘Risug’ is an alternative to surgical prosthesis, whose efficacy is not entirely denied by Indian researchers.

Michael Skinner, a reproductive specialist at Washington State University, told me, ‘As a reversible contraceptive drug, it needs further trials. Right now, this is just a method of sterilization. The effects of this injection must be tested to check reversal before it can be used as a contraceptive drug. ‘

Dr. Guha agrees. “We will not claim to be able to return it’s effects yet, but I am sure, we will be able to do so after testing humans. Right now, we call this drug a good solution for Victim. It will leave no traumatic effects on the men and there will be no sign of surgery. ‘

This year, Dr. Sharma published the results of clinical trials of the drug. The vaccine was administered to 139 married men with at least two children under the age of 41 and monitored for six months. Of these, 133 men’s wives did not become pregnant after sex. In six cases where the drug did not work, leakage was attributed to vaccine syringes or sperm transplants.

However, this seemingly low failure rate is also important for Dr. Stephanie, a researcher at Washington University. She says that this rate and the potential adverse effects of this drug may not be much different than Vasectomy. There is a need of more information in this regard. ‘

Professor says that although research on this drug has been positive so far, he believes that the number of participants in the trial is 139, and six prevention from pregnancies is not much.

She says, ‘this medicine is definitely a next step but it cannot be called a game changer.’

Indian researchers say that Risug has passed three stages of experiments on humans. And the experiments have been performed on more than 500 volunteers using the best procedures made nationwide since 1990.

More than two dozen drug-related research has been cited in three decades to clarify the efficacy of this drug in preventing pregnancy.

Researchers say that the injection will be available at a lower cost and will be effective in the long run to prevent pregnancy. He also said that the volunteers did not complain of libido disappearance or any other side effect.

India’s drug regulators are expected to give the green light for production and sale of the drug soon, and it is more likely that the Indian government will do it on its own.

It is time for men to adopt effective contraceptive methods as well. For decades, women have been carrying the burden of unplanned pregnancy.

Researchers say that pregnancy and birth risk are high. Therefore, the need for development of safe and effective contraceptive drugs for women is higher than for men. Scientific and social efforts have focused more on contraceptive methods for women.

Nearly 60 years later after the first contraceptive pill was available in the United States, women today rely on more than a dozen methods to prevent unplanned pregnancies, including pills, patches, injections, implants etc.

Dr. Sujoy Guha licensed the drug to the Parsemus Foundation, a nonprofit organization based in the American city of Berkeley, to introduce it in the United States, and another contraceptive drug, Vessel Jill, is already in clinical trials. Simultaneously, clinical trials of this drug are ongoing in six European countries. With the help of the Bill and Melinda Gates Foundation, Dr. Guha is developing a drug for women that is a vaccine and stops the pregnancy.

So will men now play their part in this process?

In masculine societies like India, the use of contraceptives is less in men. According to official data, 90% of married couples do not use condoms. Men’s vaccination rates are extremely low. After all, sterilization is the most popular method of contraception.

However, researchers believe that attitudes are changing worldwide.

Dr. says that times and attitudes are changing worldwide. One of the reasons is that men are less likely to have a role in contraception as they have very few ways to do so. The goal of this field is to give men options in this regard. Only then men will take the responsibility off from their peers and shoulder it. ”

Now it is only a matter of time before Risug will become the successful drug that men desperately need.


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